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| Fadaei-Kenarsary,Meysam; Moghaddam,Hadi Fathi; Mansouri,Seyyed Mohammad Taghi; Farbood,Yaghoob. |
| ABSTRACT Relapse is highly prevalent after detoxification and depression. Due to the advantages of venlafaxine compared with other antidepressants, it is expected that venlafaxine administration may reduce relapse after detoxification and depression. This study aimed to evaluate the effects of venlafaxine on depression-induced relapse to morphine dependence after methadone detoxification. Eighty Sprague-Dawley rats were habituated and conditioned with morphine (10 mg/kg, S.C., for 4 days). After that, primary forced swimming and conditioned place preference (CPP) were tested. They were followed by methadone (70 mg/kg/day, P.O., for 7 days) administration, extinguishing, forced swimming stress (FSS) and administration of venlafaxine (80 mg/kg/day, I.P., for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Morphine; Methadone; Depression; Relapse; Venlafaxine; Rat. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100311 |
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| Cardoso,Helena Mondardo; Padilha,Vanessa Sasso; Tocheto,Ronise; Regalin,Douglas; Gehrcke,Martielo Ivan; Oleskovicz,Nilson. |
| ABSTRACT: The present study aimed to evaluate the effects of different sedation protocols on blood pressure and echocardiographic and electrocardiographic parameters in dogs. In total, 24 male mixed-breed dogs with a mean weight of 9.87±3.0kg were used.Animals were randomly divided into four groups (n=6), which were subjected to sedation using the following protocols: acepromazine (0.05mgkg-1) and butorphanol (0.3mgkg-1) (AB); acepromazine (0.05mgkg-1)and methadone (0.5mgkg-1) (AM); acepromazine (0.03mgkg-1), methadone (0.5mgkg-1), and midazolam (0.3mgkg-1)(MAM); and methadone only (0.5mgkg-1) (M). Indirect blood pressure (BP) measurements and computerized electrocardiography (ECG) and echocardiography (ECO) were performed immediately before the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cardiac evaluation; Butorphanol; Acepromazine; Methadone; Midazolam. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016001102043 |
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| Uscategui,R.A.R.; Santos,V.J.C.; Almeida,V.T.; Barros,F.F.P.C.; Kawanami,A.E.; Cruz,N.R.N.; Feliciano,M.A.R.; Vicente,W.R.R.. |
| ABSTRACT The aim of this study was to assess the effects of chemical restraint, general anesthesia and opioid treatment on hematological components in Cuniculus paca. Eight healthy, adult, captivity female animals , underwent three laparoscopic procedures with a 15-day interval were evaluated. After physical restraint, an association of ketamine (25mg/kg) and midazolam (0.5mg/kg) was administered intramuscularly for chemical restraint. Posteriorly, anesthesia was induced and maintained with isoflurane; and randomly administered methadone (0.5mg/kg), tramadol (5mg/kg) or saline-placebo (0,1mL/kg) intramuscularly. After pharmacological restraint and in the final laparoscopy stage, venous blood samples were obtained for complete blood count, total plasma... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Isoflurane; Ketamine; Methadone; Midazolam; Rodents. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000501558 |
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| Natalini,Cláudio Corrêa; Linardi,Renata Lehn; Polydoro,Alexandre da Silva. |
| The study was done to compare the heart rate, arterial blood pressure, arterial blood gases, respiratory rate, body temperature, and behavior after subarachnoid administration of hyperbaric morphine (MorphineD10), buprenorphine (BuprenorphineD10), methadone (Methadone D10), and 10% dextrose (D10) in conscious horses. Six adult horses were studied. Treatments were administered into the lombo-sacral subarachnoid space through an epidural catheter, MorphineD10 at 0.01mg kg-1, BuprenorphineD10 at 0.001mg kg-1, MethadoneD10 at 0.01mg kg-1, and 10% dextrose as a control group. The results showed that there are minimum changes in heart and respiratory rate, blood gases, blood pressure, and body temperature after subarachnoid administration of hyperbaric opioids... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Morphine; Methadone; Buprenorphine; Hyperbaric opioid; Subarachnoid. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782006000500015 |
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